EW-7195 Catalog No.:M25722-C HEK293T cells) treatment promotes a

HEK293T cells) treatment promotes a substantial reduction in nuclear FKBP12 that is sustained across a 4-72 h time frame

is used as a cell synchronizing agent

InChi: InChI=1S/C8H7NO4S

Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

EW-7195 Catalog No.:M25722-C HEK293T cells) treatment promotes aEW 7195 is a potent and selective ALK5 (TGFR1) inhibitor with an IC50 of 4. 83 nM. EW 7195 has >300 fold selectivity for ALK5 over p38. EW 7195 efficiently inhibits TGF 1 induced Smad signaling, epithelial to mesenchymal transition (EMT) and breast tumour metastasis to the lung. Product information CAS Number: 1352609 28 9 Molecular Weight: 406. 44 Formula: C23H18N8 Chemical Name: 3 ({[5 (6 methylpyridin 2 yl) 4 {[1,2,4]triazolo[1,5 a]pyridin 6 yl} 1H